On Periodic Oscillation and Its Period of a Circadian Rhythm Model

doi:10.1007/s42967-021-00146-1

Communications on Applied Mathematics and Computation ›› 2022, Vol. 4 ›› Issue (3): 1131-1157.doi: 10.1007/s42967-021-00146-1

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On Periodic Oscillation and Its Period of a Circadian Rhythm Model

Miao Feng, Chen Zhang

Department of Mathematics, Shanghai Normal University, Shanghai 200234, China

收稿日期:2020-11-13 修回日期:2021-03-22 出版日期:2022-09-20 发布日期:2022-07-04
通讯作者: Miao Feng,E-mail:shnuMiaoFeng@163.com;Chen Zhang,E-mail:zhangchenshnu@163.com E-mail:shnuMiaoFeng@163.com;zhangchenshnu@163.com
基金资助:
This work was supported by the National Natural Science Foundation of China (NSFC) (No. 11771295).

On Periodic Oscillation and Its Period of a Circadian Rhythm Model

Miao Feng, Chen Zhang

Department of Mathematics, Shanghai Normal University, Shanghai 200234, China

Received:2020-11-13 Revised:2021-03-22 Online:2022-09-20 Published:2022-07-04
Contact: Miao Feng,E-mail:shnuMiaoFeng@163.com;Chen Zhang,E-mail:zhangchenshnu@163.com E-mail:shnuMiaoFeng@163.com;zhangchenshnu@163.com
Supported by:
This work was supported by the National Natural Science Foundation of China (NSFC) (No. 11771295).

摘要/Abstract

摘要： We theoretically study periodic oscillation and its period of a circadian rhythm model of Neurospora and provide the conditions for the existence of such a periodic oscillation by the theory of competitive dynamical systems. To present the exact expression of the unique equilibrium in terms of parameters of system, we divide them into eleven classes for the Hill coefficient $ n=1 $ or $ n=2 $, among seven classes of which nontrivial periodic oscillations exist. Numerical simulations are made among the seven classes and the models with the Hill coefficient $ n=3 $ or $ n=4 $ to reveal the influence of parameter variation on periodic oscillations and their periods. The results show that their periods of the periodic oscillations are approximately 21.5 h, which coincides with the known experiment result observed in constant darkness.

关键词: Rhythm model, $K_{m}$ -type competition system, Periodic oscillation, Period

Abstract: We theoretically study periodic oscillation and its period of a circadian rhythm model of Neurospora and provide the conditions for the existence of such a periodic oscillation by the theory of competitive dynamical systems. To present the exact expression of the unique equilibrium in terms of parameters of system, we divide them into eleven classes for the Hill coefficient $ n=1 $ or $ n=2 $, among seven classes of which nontrivial periodic oscillations exist. Numerical simulations are made among the seven classes and the models with the Hill coefficient $ n=3 $ or $ n=4 $ to reveal the influence of parameter variation on periodic oscillations and their periods. The results show that their periods of the periodic oscillations are approximately 21.5 h, which coincides with the known experiment result observed in constant darkness.

Key words: Rhythm model, $K_{m}$ -type competition system, Periodic oscillation, Period

中图分类号:

Miao Feng, Chen Zhang. On Periodic Oscillation and Its Period of a Circadian Rhythm Model[J]. Communications on Applied Mathematics and Computation, 2022, 4(3): 1131-1157.

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On Periodic Oscillation and Its Period of a Circadian Rhythm Model

On Periodic Oscillation and Its Period of a Circadian Rhythm Model

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